Rejuran Salmon DNA: The Popular Korean Skin Treatment Now Available in Sydney

Rejuran is a skin rejuvenation treatment containing polynucleotides (PN) — purified fragments of DNA derived from salmon.

When introduced into the dermis using fine injections, these polynucleotides support cellular repair processes and stimulate fibroblast activity. Fibroblasts play an important role in the production of collagen and other components that contribute to the structure and quality of the skin.

For this reason, Rejuran is primarily used to improve skin quality rather than facial volume or shape.

Depending on individual concerns and suitability, Rejuran may be considered for:

• Fine lines and wrinkles
• Loss of skin elasticity
• Dehydrated or dull-looking skin
• Uneven skin texture
• Enlarged pores
• Acne scarring
• A compromised skin barrier
• Signs of ageing around the eyes

Rejuran originated in South Korea and has become a well-known treatment within Korean aesthetic medicine.

Its popularity also reflects a broader Korean skincare philosophy that often focuses on maintaining and improving skin quality rather than simply treating individual lines or wrinkles.

Instead of creating additional facial volume, Rejuran works within the skin and is designed to support regeneration, collagen production and overall skin quality.

This has also contributed to growing international interest in Rejuran as Korean skincare and aesthetic treatments have become increasingly popular outside Korea.

This is one of the most common questions surrounding Rejuran — and the reason it is sometimes referred to online as the “salmon sperm treatment” or “salmon sperm facial.”

The polynucleotides used in Rejuran are derived from salmon milt, which is the reproductive fluid of male salmon.

However, salmon milt itself is not injected into the skin.

It undergoes a controlled purification process that isolates specific DNA fragments known as polynucleotides. These purified polynucleotides are the component used in the Rejuran treatment.

This distinction is important, as terms such as “salmon sperm facial” are commonly used online but do not accurately describe what is administered during treatment.

Rejuran polynucleotides are designed to support the skin’s natural repair and regeneration mechanisms.

Once delivered into the dermis, the purified DNA fragments can stimulate fibroblast activity and encourage collagen production while supporting tissue repair.

Over time, this may help improve the appearance of:

• Fine lines
• Skin texture
• Crepiness
• Elasticity
• Dehydration
• Dull-looking skin

Changes occur gradually as the skin responds to treatment and collagen production develops over the following weeks.

The under-eye area is one of the most popular areas treated with Rejuran.

Skin around the eyes is naturally thin and delicate. With age, changes in collagen, elasticity and skin quality can make fine lines, crepiness and dark circles more noticeable.

Rejuran can be introduced directly into this delicate area using fine injections, with the aim of improving the quality and structure of the skin rather than adding significant volume.

Depending on the individual, Rejuran under-eye treatment may be considered for concerns including:

• Fine lines
• Crow’s feet
• Crepey under-eye skin
• Reduced elasticity
• Dark circles associated with skin quality

It is important to remember that dark circles can have several different causes. A consultation is therefore required to determine whether Rejuran is appropriate for the particular concern.

Before treatment, a face-to-face consultation and skin assessment are performed to determine whether Rejuran is suitable for you.

On the day of treatment, the skin is cleansed and the treatment area is numbed for comfort.

Rejuran is then delivered into the dermis through a series of fine injections across the treatment area.

Small raised areas may initially be visible at the injection sites. Mild redness or swelling can also occur following treatment and will generally settle as the product disperses and the skin recovers.

The appropriate number of treatments depends on the individual, their skin concerns and their treatment goals.

At LookFresh, most patients are recommended an initial course of approximately three to four Rejuran treatments, usually spaced around three to four weeks apart.

Maintenance treatments may then be recommended depending on the individual response and treatment plan.

Before-and-after images of Rejuran Salmon DNA treatment often focus on changes in skin quality rather than dramatic alterations to facial appearance.

Depending on the treatment area and individual response, changes may include improvements in the appearance of fine lines, skin texture, crepiness and greater radiance and glow.

For the under-eye area in particular, treatment aims to improve the quality of the delicate skin surrounding the eyes.

Before-and-after photographs should always be considered in the context of individual variation. Another patient’s outcome cannot predict the result that a different person will achieve.